Orphanin FQ/nociceptin suppresses motor activity through an action along the mesoaccumbens axis in rats

OBJECTIVE: Intracerebroventricular administration of orphanin FQ/nociceptin (OFQ/N), the endogenous agonist ligand of the opioid receptor-like (ORL-1) receptor, decreases extracellular levels of dopamine and suppresses motor activity. The presence of the ORL-1 receptor on mesoaccumbal and nigrostria...

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Bibliografske podrobnosti
Main Authors: Narayanan, Shridhar, Lam, Hoa, Carroll, F. Ivy, Lutfy, Kabirullah
Format: Artigo
Jezik:Inglês
Izdano: 2004
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC383343/
https://ncbi.nlm.nih.gov/pubmed/15069465
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