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Nociceptin/orphanin FQ suppresses the excitability of neurons in the ventromedial nucleus of the hypothalamus

ABSTRACT: Nociceptin or orphanin FQ (N/OFQ) stimulates food intake when injected into the ventromedial nucleus of the hypothalamus (VMN). The VMN negatively regulates energy balance in part by tonically activating proopiomelanocortin arcuate neurons, thereby suppressing food intake. However, it is n...

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Main Authors: Chee, Melissa J, Price, Christopher J, Statnick, Michael A, Colmers, William F
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145927/
https://ncbi.nlm.nih.gov/pubmed/21502286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.208819
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