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Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats
RATIONALE: Orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the opioid receptor-like (ORL-1) receptor, shows similarities to dynorphin A (1−17) in structure and functions. Dynorphin and other kappa opioid receptor agonists have been shown to block cocaine sensitization. OBJECTIVE: The presen...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2002
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2268895/ https://ncbi.nlm.nih.gov/pubmed/12404079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-002-1192-1 |
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