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Orphanin FQ/nociceptin blocks cocaine-induced behavioral sensitization in rats

RATIONALE: Orphanin FQ/nociceptin (OFQ/N), the endogenous ligand of the opioid receptor-like (ORL-1) receptor, shows similarities to dynorphin A (1−17) in structure and functions. Dynorphin and other kappa opioid receptor agonists have been shown to block cocaine sensitization. OBJECTIVE: The presen...

詳細記述

保存先:
書誌詳細
主要な著者: Lutfy, Kabirullah, Khaliq, Imran, Maidment, Nigel T., Carroll, F. Ivy
フォーマット: Artigo
言語:Inglês
出版事項: 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268895/
https://ncbi.nlm.nih.gov/pubmed/12404079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-002-1192-1
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