TERT Promoter Mutations Are Frequent in Cutaneous Basal Cell Carcinoma and Squamous Cell Carcinoma

Activating mutations in the TERT promoter were recently identified in up to 71% of cutaneous melanoma. Subsequent studies found TERT promoter mutations in a wide array of other major human cancers. TERT promoter mutations lead to increased expression of telomerase, which maintains telomere length an...

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Detalhes bibliográficos
Main Authors: Griewank, Klaus G., Murali, Rajmohan, Schilling, Bastian, Schimming, Tobias, Möller, Inga, Moll, Iris, Schwamborn, Marion, Sucker, Antje, Zimmer, Lisa, Schadendorf, Dirk, Hillen, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832433/
https://ncbi.nlm.nih.gov/pubmed/24260374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080354
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