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Frequent Occurrence of NRAS and BRAF Mutations in Human Acral Naevi

Acral naevi are benign melanocytic tumors occurring at acral sites. Occasionally they can progress to become malignant tumors (melanomas). The genetics of acral naevi have not been assessed in larger studies. In our study, a large cohort of 130 acral naevi was screened for gene mutations known to be...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Jansen, Philipp, Cosgarea, Ioana, Murali, Rajmohan, Möller, Inga, Sucker, Antje, Franklin, Cindy, Paschen, Annette, Zaremba, Anne, Brinker, Titus J., Stoffels, Ingo, Schadendorf, Dirk, Klode, Joachim, Hadaschik, Eva, Griewank, Klaus G.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520878/
https://ncbi.nlm.nih.gov/pubmed/30995742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040546
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