TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

BACKGROUND: Recently, TERT promoter mutations were identified at high frequencies in cutaneous melanoma tumor samples and cell lines. The mutations were found to have a UV-signature and to lead to increased TERT gene expression. We analyzed a large cohort of melanoma patients for the presence and di...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Griewank, Klaus G., Murali, Rajmohan, Puig-Butille, Joan Anton, Schilling, Bastian, Livingstone, Elisabeth, Potrony, Miriam, Carrera, Cristina, Schimming, Tobias, Möller, Inga, Schwamborn, Marion, Sucker, Antje, Hillen, Uwe, Badenas, Celia, Malvehy, Josep, Zimmer, Lisa, Scherag, André, Puig, Susana, Schadendorf, Dirk
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2014
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200061/
https://ncbi.nlm.nih.gov/pubmed/25217772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju246
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