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TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

BACKGROUND: Recently, TERT promoter mutations were identified at high frequencies in cutaneous melanoma tumor samples and cell lines. The mutations were found to have a UV-signature and to lead to increased TERT gene expression. We analyzed a large cohort of melanoma patients for the presence and di...

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Hlavní autoři: Griewank, Klaus G., Murali, Rajmohan, Puig-Butille, Joan Anton, Schilling, Bastian, Livingstone, Elisabeth, Potrony, Miriam, Carrera, Cristina, Schimming, Tobias, Möller, Inga, Schwamborn, Marion, Sucker, Antje, Hillen, Uwe, Badenas, Celia, Malvehy, Josep, Zimmer, Lisa, Scherag, André, Puig, Susana, Schadendorf, Dirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200061/
https://ncbi.nlm.nih.gov/pubmed/25217772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju246
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