TERT Promoter Mutation Status as an Independent Prognostic Factor in Cutaneous Melanoma

BACKGROUND: Recently, TERT promoter mutations were identified at high frequencies in cutaneous melanoma tumor samples and cell lines. The mutations were found to have a UV-signature and to lead to increased TERT gene expression. We analyzed a large cohort of melanoma patients for the presence and di...

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Bibliografiske detaljer
Main Authors: Griewank, Klaus G., Murali, Rajmohan, Puig-Butille, Joan Anton, Schilling, Bastian, Livingstone, Elisabeth, Potrony, Miriam, Carrera, Cristina, Schimming, Tobias, Möller, Inga, Schwamborn, Marion, Sucker, Antje, Hillen, Uwe, Badenas, Celia, Malvehy, Josep, Zimmer, Lisa, Scherag, André, Puig, Susana, Schadendorf, Dirk
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4200061/
https://ncbi.nlm.nih.gov/pubmed/25217772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju246
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