Neuroprotective Sirtuin ratio reversed by ApoE4

The canonical pathogenesis of Alzheimer’s disease links the expression of apolipoprotein E ε4 allele (ApoE) to amyloid precursor protein (APP) processing and Aβ peptide accumulation by a set of mechanisms that is incompletely defined. The development of a simple system that focuses not on a single v...

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Bibliographische Detailangaben
Hauptverfasser: Theendakara, Veena, Patent, Alexander, Peters Libeu, Clare A., Philpot, Brittany, Flores, Sonia, Descamps, Olivier, Poksay, Karen S., Zhang, Qiang, Cailing, Gabriellee, Hart, Matthew, John, Varghese, Rao, Rammohan V., Bredesen, Dale E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831497/
https://ncbi.nlm.nih.gov/pubmed/24145446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314145110
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