Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice

Gene-associated with retinoid-interferon induced mortality-19 (GRIM-19), a STAT3-inhibitory protein, was isolated as a growth-suppressive gene product using a genome-wide expression knockdown screen. We and others have shown a loss of expression and occurrence of mutations in the GRIM-19 gene in a v...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Kalakonda, Sudhakar, Nallar, Shreeram C., Jaber, Sausan, Keay, Susan K., Rorke, Ellen, Munivenkatappa, Raghava, Lindner, Daniel J., Fiskum, Gary M., Kalvakolanu, Dhananjaya V.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831468/
https://ncbi.nlm.nih.gov/pubmed/24145455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303760110
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky