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Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice
Gene-associated with retinoid-interferon induced mortality-19 (GRIM-19), a STAT3-inhibitory protein, was isolated as a growth-suppressive gene product using a genome-wide expression knockdown screen. We and others have shown a loss of expression and occurrence of mutations in the GRIM-19 gene in a v...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831468/ https://ncbi.nlm.nih.gov/pubmed/24145455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303760110 |
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