GRIM-19 mutations fail to inhibit v-Src-induced oncogenesis

The non-receptor tyrosine kinase Src is a major player in multiple physiological responses including growth, survival and differentiation. Overexpression and/or oncogenic mutation in the Src gene have been documented in human tumors. The v-Src protein is an oncogenic mutant of Src, which promotes ce...

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Hlavní autoři: Kalakonda, Sudhakar, Nallar, Shreeram C., Lindner, Daniel J., Sun, Peng, Lorenz, Robert R., Lamarre, Eric, Reddy, Sekhar P., Kalvakolanu, Dhananjaya V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916943/
https://ncbi.nlm.nih.gov/pubmed/23851499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.271
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