A Novel Hap1–Tsc1 Interaction Regulates Neuronal mTORC1 Signaling and Morphogenesis in the Brain

Tuberous sclerosis complex (TSC) is a leading genetic cause of autism. The TSC proteins Tsc1 and Tsc2 control the mTORC1 signaling pathway in diverse cells, but how the mTORC1 pathway is specifically regulated in neurons remains to be elucidated. Here, using an interaction proteomics approach in neu...

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Bibliografske podrobnosti
Main Authors: Mejia, Luis A., Litterman, Nadia, Ikeuchi, Yoshiho, de la Torre-Ubieta, Luis, Bennett, Eric J., Zhang, Chi, Harper, J. Wade, Bonni, Azad
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2013
Teme:
Brief Communications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828457/
https://ncbi.nlm.nih.gov/pubmed/24227713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2290-13.2013
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