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The XLID Protein PQBP1 and the GTPase Dynamin 2 Define a Signaling Link that Orchestrates Ciliary Morphogenesis in Postmitotic Neurons
Intellectual disability is a prevalent developmental disorder of cognition that remains incurable. Here, we report that knockdown of the X-linked intellectual disability (XLID) protein polyglutamine binding protein 1 (PQBP1) in neurons profoundly impairs the morphogenesis of the primary cilium, incl...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013279/ https://ncbi.nlm.nih.gov/pubmed/23994472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.042 |
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