The XLID Protein PQBP1 and the GTPase Dynamin 2 Define a Signaling Link that Orchestrates Ciliary Morphogenesis in Postmitotic Neurons

Intellectual disability is a prevalent developmental disorder of cognition that remains incurable. Here, we report that knockdown of the X-linked intellectual disability (XLID) protein polyglutamine binding protein 1 (PQBP1) in neurons profoundly impairs the morphogenesis of the primary cilium, incl...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ikeuchi, Yoshiho, de la Torre-Ubieta, Luis, Matsuda, Takahiko, Steen, Hanno, Okazawa, Hitoshi, Bonni, Azad
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013279/
https://ncbi.nlm.nih.gov/pubmed/23994472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.042
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky