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Limited Promiscuity of HLA-DRB1 Presented Peptides Derived of Blood Coagulation Factor VIII
The formation of inhibitory antibodies directed against coagulation factor VIII (FVIII) is a severe complication in the treatment of hemophilia A patients. The induction of anti-FVIII antibodies is a CD4(+) T cell-dependent process. Activation of FVIII-specific CD4(+) T cells is dependent on the pre...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828219/ https://ncbi.nlm.nih.gov/pubmed/24244658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080239 |
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