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ITE, A Novel Endogenous Nontoxic Aryl Hydrocarbon Receptor Ligand, Efficiently Suppresses EAU and T-Cell–Mediated Immunity

PURPOSE. Ligands for aryl hydrocarbon receptor (AHR), such as dioxins, are highly toxic. One such ligand, TCDD, was found to exert potent immunosuppressive capacities in mice developing pathogenic autoimmune processes, including EAU, but its toxicity makes it unusable for humans. A recently identifi...

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מידע ביבליוגרפי
Main Authors: Nugent, Lindsey F., Shi, Guangpu, Vistica, Barbara P., Ogbeifun, Osato, Hinshaw, Samuel J. H., Gery, Igal
פורמט: Artigo
שפה:Inglês
יצא לאור: The Association for Research in Vision and Ophthalmology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828045/
https://ncbi.nlm.nih.gov/pubmed/24150760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-11479
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