The Aryl Hydrocarbon Receptor Ligand ITE Inhibits TGFβ1-Induced Human Myofibroblast Differentiation

Fibrosis can occur in any human tissue when the normal wound healing response is amplified. Such amplification results in fibroblast proliferation, myofibroblast differentiation, and excessive extracellular matrix deposition. Occurrence of these sequelae in organs such as the eye or lung can result...

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Detalhes bibliográficos
Main Authors: Lehmann, Geniece M., Xi, Xia, Kulkarni, Ajit A., Olsen, Keith C., Pollock, Stephen J., Baglole, Carolyn J., Gupta, Shikha, Casey, Ann E., Huxlin, Krystel R., Sime, Patricia J., Feldon, Steven E., Phipps, Richard P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078465/
https://ncbi.nlm.nih.gov/pubmed/21406171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.025
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