The Aryl Hydrocarbon Receptor Ligand ITE Inhibits TGFβ1-Induced Human Myofibroblast Differentiation

Fibrosis can occur in any human tissue when the normal wound healing response is amplified. Such amplification results in fibroblast proliferation, myofibroblast differentiation, and excessive extracellular matrix deposition. Occurrence of these sequelae in organs such as the eye or lung can result...

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Autors principals: Lehmann, Geniece M., Xi, Xia, Kulkarni, Ajit A., Olsen, Keith C., Pollock, Stephen J., Baglole, Carolyn J., Gupta, Shikha, Casey, Ann E., Huxlin, Krystel R., Sime, Patricia J., Feldon, Steven E., Phipps, Richard P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2011
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078465/
https://ncbi.nlm.nih.gov/pubmed/21406171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.12.025
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