RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs

Triple negative breast cancer (TNBC) includes basal-like and claudin-low subtypes for which only chemotherapy and radiation therapy are currently available. The retinoblastoma (RB1) tumor suppressor is frequently lost in human TNBC. Knockdown of RB1 in luminal BC cells was shown to affect response t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Robinson, Tyler J. W., Liu, Jeff C., Vizeacoumar, Frederick, Sun, Thomas, Maclean, Neil, Egan, Sean E., Schimmer, Aaron D., Datti, Alessandro, Zacksenhaus, Eldad
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3827056/
https://ncbi.nlm.nih.gov/pubmed/24265703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078641
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi