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Chromatin marks identify critical cell types for fine mapping complex trait variants

If trait-associated variants alter regulatory regions, then they should fall within chromatin marks in relevant cell types. However, it is unclear which of the many marks are most useful in defining cell types associated with disease and fine mapping variants. We hypothesized that informative marks...

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Autori principali: Trynka, Gosia, Sandor, Cynthia, Han, Buhm, Xu, Han, Stranger, Barbara E, Liu, X Shirley, Raychaudhuri, Soumya
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826950/
https://ncbi.nlm.nih.gov/pubmed/23263488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2504
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