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Chromatin marks identify critical cell types for fine mapping complex trait variants

If trait-associated variants alter regulatory regions, then they should fall within chromatin marks in relevant cell types. However, it is unclear which of the many marks are most useful in defining cell types associated with disease and fine mapping variants. We hypothesized that informative marks...

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Main Authors: Trynka, Gosia, Sandor, Cynthia, Han, Buhm, Xu, Han, Stranger, Barbara E, Liu, X Shirley, Raychaudhuri, Soumya
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826950/
https://ncbi.nlm.nih.gov/pubmed/23263488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2504
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