Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci

Identifying genomic annotations that differentiate causal from trait-associated variants is essential to fine mapping disease loci. Although many studies have identified non-coding functional annotations that overlap disease-associated variants, these annotations often colocalize, complicating the a...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Trynka, Gosia, Westra, Harm-Jan, Slowikowski, Kamil, Hu, Xinli, Xu, Han, Stranger, Barbara E., Klein, Robert J., Han, Buhm, Raychaudhuri, Soumya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572568/
https://ncbi.nlm.nih.gov/pubmed/26140449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.05.016
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