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Tissue-Specific Enrichment of Lymphoma Risk Loci in Regulatory Elements

Though numerous polymorphisms have been associated with risk of developing lymphoma, how these variants function to promote tumorigenesis is poorly understood. Here, we report that lymphoma risk SNPs, especially in the non-Hodgkin’s lymphoma subtype chronic lymphocytic leukemia, are significantly en...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hayes, James E., Trynka, Gosia, Vijai, Joseph, Offit, Kenneth, Raychaudhuri, Soumya, Klein, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589387/
https://ncbi.nlm.nih.gov/pubmed/26422229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139360
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