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Human Serotonin 5-HT(2C) G Protein-Coupled Receptor Homology Model from the β(2) Adrenoceptor Structure: Ligand Docking and Mutagenesis Studies
Activation of the serotonin (5-hydroxytryptamine, 5-HT) 5HT(2C) G protein-coupled receptor (GPCR) is proposed as novel pharmacotherapy for obesity and neuropsychiatric disorders. In contrast, activation of the 5-HT(2A) and 5-HT(2B) GPCRs is associated with untoward hallucinogenic and cardiopulmonary...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826658/ https://ncbi.nlm.nih.gov/pubmed/24244046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/qua.23231 |
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