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Synthesis, Activity and Structure-Activity Relationship of Noroviral Protease Inhibitors

The protease of norovirus, an important human pathogen, is essential for the viral replication and, therefore, represents a potential drug target. A series of tripeptide-based inhibitors of the protease were designed, synthesized and tested, among which several potent inhibitors were identified with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Deng, Lisheng, Muhaxhiri, Zana, Estes, Mary K., Palzkill, Timothy, Prasad, B. V. Venkataram, Song, Yongcheng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826262/
https://ncbi.nlm.nih.gov/pubmed/24244836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00219E
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