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Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus
Norwalk virus (NV), the prototype human calicivirus, is the leading cause of nonbacterial acute gastroenteritis. The NV protease cleaves the polyprotein encoded by open reading frame 1 of the viral genome at five nonhomologous sites, releasing six nonstructural proteins that are essential for viral...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624372/ https://ncbi.nlm.nih.gov/pubmed/23365454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02869-12 |
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