Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Norwalk virus (NV), the prototype human calicivirus, is the leading cause of nonbacterial acute gastroenteritis. The NV protease cleaves the polyprotein encoded by open reading frame 1 of the viral genome at five nonhomologous sites, releasing six nonstructural proteins that are essential for viral...

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Bibliographische Detailangaben
Hauptverfasser: Muhaxhiri, Zana, Deng, Lisheng, Shanker, Sreejesh, Sankaran, Banumathi, Estes, Mary K., Palzkill, Timothy, Song, Yongcheng, Prasad, B. V. Venkataram
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624372/
https://ncbi.nlm.nih.gov/pubmed/23365454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02869-12
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