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Synthesis, Activity and Structure-Activity Relationship of Noroviral Protease Inhibitors
The protease of norovirus, an important human pathogen, is essential for the viral replication and, therefore, represents a potential drug target. A series of tripeptide-based inhibitors of the protease were designed, synthesized and tested, among which several potent inhibitors were identified with...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826262/ https://ncbi.nlm.nih.gov/pubmed/24244836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3MD00219E |
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