GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site

Human noroviruses (NoVs) are the main cause of epidemic and sporadic gastroenteritis. Phylogenetically, noroviruses are divided into seven genogroups, with each divided into multiple genotypes. NoVs belonging to genogroup II and genotype 4 (GII.4) are globally most prevalent. Genetic diversity among...

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Bibliographic Details
Published in:J Virol
Main Authors: Viskovska, Mariya A., Zhao, Boyang, Shanker, Sreejesh, Choi, Jae-Mun, Deng, Lisheng, Song, Yongchen, Palzkill, Timothy, Hu, Liya, Estes, Mary K., Venkataram Prasad, B. V.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2019
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401421/
https://ncbi.nlm.nih.gov/pubmed/30626675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01479-18
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