GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site

Human noroviruses (NoVs) are the main cause of epidemic and sporadic gastroenteritis. Phylogenetically, noroviruses are divided into seven genogroups, with each divided into multiple genotypes. NoVs belonging to genogroup II and genotype 4 (GII.4) are globally most prevalent. Genetic diversity among...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Viskovska, Mariya A., Zhao, Boyang, Shanker, Sreejesh, Choi, Jae-Mun, Deng, Lisheng, Song, Yongchen, Palzkill, Timothy, Hu, Liya, Estes, Mary K., Venkataram Prasad, B. V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6401421/
https://ncbi.nlm.nih.gov/pubmed/30626675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01479-18
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