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Phosphorylation and Degradation of S6K1 (p70S6K1) in Response to Persistent JNK1 Activation
S6K (ribosomal S6 kinase p70, p70S6K) activation requires phosphorylation at two stages. The first phosphorylation is independent of insulin stimulation and mediated by an unknown kinase. The second phosphorylation is mediated by mTOR in insulin dependent manner. In this study, we identified JNK1 (c...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825840/ https://ncbi.nlm.nih.gov/pubmed/23816567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.06.013 |
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