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Inactivation of NF-κB p50 Leads to Insulin Sensitization in Liver through Post-translational Inhibition of p70S6K
In this study, we investigated the metabolic phenotype of the NF-κB p50 knock-out (p50-KO) mice. Compared with wild type mice, the p50-KO mice had an increase in food intake, but a decrease in body fat content. On chow diet, their blood glucose dropped much more than the wild type (WT) mice in the i...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2709339/ https://ncbi.nlm.nih.gov/pubmed/19433583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007260 |
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