Inactivation of NF-κB p50 Leads to Insulin Sensitization in Liver through Post-translational Inhibition of p70S6K

In this study, we investigated the metabolic phenotype of the NF-κB p50 knock-out (p50-KO) mice. Compared with wild type mice, the p50-KO mice had an increase in food intake, but a decrease in body fat content. On chow diet, their blood glucose dropped much more than the wild type (WT) mice in the i...

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Bibliographische Detailangaben
Hauptverfasser: Gao, Zhanguo, Yin, Jun, Zhang, Jin, He, Qing, McGuinness, Owen P., Ye, Jianping
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Metabolism and Bioenergetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709339/
https://ncbi.nlm.nih.gov/pubmed/19433583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.007260
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