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Likelihood-based classification of cryo-EM images using FREALIGN
We describe an implementation of maximum likelihood classification for single particle electron cryo-microscopy that is based on the FREALIGN software. Particle alignment parameters are determined by maximizing a joint likelihood that can include hierarchical priors, while classification is performe...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824613/ https://ncbi.nlm.nih.gov/pubmed/23872434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.07.005 |
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