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Likelihood-based classification of cryo-EM images using FREALIGN

We describe an implementation of maximum likelihood classification for single particle electron cryo-microscopy that is based on the FREALIGN software. Particle alignment parameters are determined by maximizing a joint likelihood that can include hierarchical priors, while classification is performe...

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Hlavní autoři: Lyumkis, Dmitry, Brilot, Axel F., Theobald, Douglas L., Grigorieff, Nikolaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824613/
https://ncbi.nlm.nih.gov/pubmed/23872434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.07.005
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