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Analysis of Discrete Local Variability and Structural Covariance in Macromolecular Assemblies using Cryo-EM and Focused Classification
Single-particle electron cryo-microscopy and computational image classification can be used to analyze structural variability in macromolecules and their assemblies. In some cases, a particle may contain different regions that each display a range of distinct conformations. We have developed strateg...
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| 出版年: | Ultramicroscopy |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6476647/ https://ncbi.nlm.nih.gov/pubmed/30528101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ultramic.2018.11.016 |
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