Movies of ice-embedded particles enhance resolution in electron cryo-microscopy

Low-dose images obtained by electron cryo-microscopy (cryo-EM) are often affected by blurring caused by sample motion during electron beam exposure, degrading signal especially at high resolution. We show here that we can align frames of movies, recorded with a direct electron detector during beam e...

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Bibliographische Detailangaben
Hauptverfasser: Campbell, Melody G., Cheng, Anchi, Brilot, Axel F., Moeller, Arne, Lyumkis, Dmitry, Veesler, David, Pan, Junhua, Harrison, Stephen C., Potter, Clinton S., Carragher, Bridget, Grigorieff, Nikolaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510009/
https://ncbi.nlm.nih.gov/pubmed/23022349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.026
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