Movies of ice-embedded particles enhance resolution in electron cryo-microscopy

Low-dose images obtained by electron cryo-microscopy (cryo-EM) are often affected by blurring caused by sample motion during electron beam exposure, degrading signal especially at high resolution. We show here that we can align frames of movies, recorded with a direct electron detector during beam e...

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Detalhes bibliográficos
Main Authors: Campbell, Melody G., Cheng, Anchi, Brilot, Axel F., Moeller, Arne, Lyumkis, Dmitry, Veesler, David, Pan, Junhua, Harrison, Stephen C., Potter, Clinton S., Carragher, Bridget, Grigorieff, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510009/
https://ncbi.nlm.nih.gov/pubmed/23022349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.026
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