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Contributions of degradation and brain-to-blood elimination across the blood–brain barrier to cerebral clearance of human amyloid-β peptide(1-40) in mouse brain

The purpose of the present study was to estimate the relative contributions of degradation and brain-to-blood elimination processes to the clearance of microinjected human amyloid-β peptide(1-40) (hAβ(1-40)) from mouse cerebral cortex, using a solid-phase extraction method together with a newly deve...

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Bibliografski detalji
Glavni autori: Ito, Shingo, Matsumiya, Kohta, Ohtsuki, Sumio, Kamiie, Junichi, Terasaki, Tetsuya
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824175/
https://ncbi.nlm.nih.gov/pubmed/23963369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.125
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