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1α,25-Dihydroxyvitamin D(3 )enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier

BACKGROUND: Cerebrovascular dysfunction has been considered to cause impairment of cerebral amyloid-β peptide (Aβ) clearance across the blood-brain barrier (BBB). Further, low levels of vitamin D are associated with increased risk of Alzheimer's disease, as well as vascular dysfunction. The pur...

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Detalhes bibliográficos
Main Authors: Ito, Shingo, Ohtsuki, Sumio, Nezu, Yasuko, Koitabashi, Yusuke, Murata, Sho, Terasaki, Tetsuya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3162579/
https://ncbi.nlm.nih.gov/pubmed/21740543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-8-20
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