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Contributions of degradation and brain-to-blood elimination across the blood–brain barrier to cerebral clearance of human amyloid-β peptide(1-40) in mouse brain
The purpose of the present study was to estimate the relative contributions of degradation and brain-to-blood elimination processes to the clearance of microinjected human amyloid-β peptide(1-40) (hAβ(1-40)) from mouse cerebral cortex, using a solid-phase extraction method together with a newly deve...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824175/ https://ncbi.nlm.nih.gov/pubmed/23963369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.125 |
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