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The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration

The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC stimulates the activity of the Cdc42- and Rac1-specific guanine nucleotide exchange factor Asef and promotes the migration and invasion of colorectal tumor cells. Furthermore, Asef is ove...

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Main Authors: Furukawa, Shiori, Kawasaki, Yoshihiro, Miyamoto, Masaya, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823710/
https://ncbi.nlm.nih.gov/pubmed/24244701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080609
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