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REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis

The transcription factor GATA6 is a critical regulator of cell proliferation and development in the gastrointestinal tract. We have recently reported that GATA6 induces the expression of the intestinal stem cell marker LGR5 and enhances the clonogenicity and tumorigenicity of colon cancer cells, but...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawasaki, Yoshihiro, Matsumura, Kosuke, Miyamoto, Masaya, Tsuji, Shinnosuke, Okuno, Masumi, Suda, Sakiko, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585703/
https://ncbi.nlm.nih.gov/pubmed/26387746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14291
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