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REG4 is a transcriptional target of GATA6 and is essential for colorectal tumorigenesis

The transcription factor GATA6 is a critical regulator of cell proliferation and development in the gastrointestinal tract. We have recently reported that GATA6 induces the expression of the intestinal stem cell marker LGR5 and enhances the clonogenicity and tumorigenicity of colon cancer cells, but...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Kawasaki, Yoshihiro, Matsumura, Kosuke, Miyamoto, Masaya, Tsuji, Shinnosuke, Okuno, Masumi, Suda, Sakiko, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585703/
https://ncbi.nlm.nih.gov/pubmed/26387746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14291
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