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The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration
The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC stimulates the activity of the Cdc42- and Rac1-specific guanine nucleotide exchange factor Asef and promotes the migration and invasion of colorectal tumor cells. Furthermore, Asef is ove...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823710/ https://ncbi.nlm.nih.gov/pubmed/24244701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080609 |
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