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The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration

The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC stimulates the activity of the Cdc42- and Rac1-specific guanine nucleotide exchange factor Asef and promotes the migration and invasion of colorectal tumor cells. Furthermore, Asef is ove...

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Detalhes bibliográficos
Main Authors: Furukawa, Shiori, Kawasaki, Yoshihiro, Miyamoto, Masaya, Hiyoshi, Masaya, Kitayama, Joji, Akiyama, Tetsu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823710/
https://ncbi.nlm.nih.gov/pubmed/24244701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080609
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