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Divergent evolution of protein conformational dynamics in dihydrofolate reductase

Molecular evolution is driven by mutations, which may affect the fitness of an organism and are then subject to natural selection or genetic drift. Analysis of primary protein sequences and tertiary structures has yielded valuable insights into the evolution of protein function, but little is known...

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書誌詳細
主要な著者: Bhabha, Gira, Ekiert, Damian C., Jennewein, Madeleine, Zmasek, Christian M., Tuttle, Lisa M., Kroon, Gerard, Dyson, H. Jane, Godzik, Adam, Wilson, Ian A., Wright, Peter E.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823643/
https://ncbi.nlm.nih.gov/pubmed/24077226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2676
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