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The RasGAP Gene, RASAL2, is a Tumor and Metastasis Suppressor
RAS genes are commonly mutated in cancer; however, RAS mutations are rare in breast cancer, despite the fact that Ras and ERK are frequently hyperactivated. Here we report that the RasGAP gene, RASAL2, functions as a tumor and metastasis suppressor. RASAL2 is mutated or suppressed in human breast ca...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822334/ https://ncbi.nlm.nih.gov/pubmed/24029233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.08.004 |
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