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Loss of RasGAP tumor suppressors underlie the aggressive nature of luminal B breast cancers

Luminal breast cancers are typically estrogen receptor positive and generally have the best prognosis. However, a subset of luminal tumors, namely luminal B cancers, frequently metastasize and recur. Unfortunately, the causal events that drive their progression are unknown and therefore it is diffic...

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Dades bibliogràfiques
Publicat a:Cancer Discov
Autors principals: Olsen, Sarah Naomi, Wronski, Ania, Castaño, Zafira, Dake, Benjamin, Malone, Clare, De Raedt, Thomas, Enos, Miriam, DeRose, Yoko S., Zhou, Wenhui, Guerra, Stephanie, Loda, Massimo, Welm, Alana, Partridge, Ann H., McAllister, Sandra S., Kuperwasser, Charlotte, Cichowski, Karen
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461361/
https://ncbi.nlm.nih.gov/pubmed/27974415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0520
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