Loss of RasGAP tumor suppressors underlie the aggressive nature of luminal B breast cancers

Luminal breast cancers are typically estrogen receptor positive and generally have the best prognosis. However, a subset of luminal tumors, namely luminal B cancers, frequently metastasize and recur. Unfortunately, the causal events that drive their progression are unknown and therefore it is diffic...

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Detalhes bibliográficos
Publicado no:Cancer Discov
Main Authors: Olsen, Sarah Naomi, Wronski, Ania, Castaño, Zafira, Dake, Benjamin, Malone, Clare, De Raedt, Thomas, Enos, Miriam, DeRose, Yoko S., Zhou, Wenhui, Guerra, Stephanie, Loda, Massimo, Welm, Alana, Partridge, Ann H., McAllister, Sandra S., Kuperwasser, Charlotte, Cichowski, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461361/
https://ncbi.nlm.nih.gov/pubmed/27974415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0520
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