Loss of RasGAP tumor suppressors underlie the aggressive nature of luminal B breast cancers

Luminal breast cancers are typically estrogen receptor positive and generally have the best prognosis. However, a subset of luminal tumors, namely luminal B cancers, frequently metastasize and recur. Unfortunately, the causal events that drive their progression are unknown and therefore it is diffic...

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Publicado en:Cancer Discov
Main Authors: Olsen, Sarah Naomi, Wronski, Ania, Castaño, Zafira, Dake, Benjamin, Malone, Clare, De Raedt, Thomas, Enos, Miriam, DeRose, Yoko S., Zhou, Wenhui, Guerra, Stephanie, Loda, Massimo, Welm, Alana, Partridge, Ann H., McAllister, Sandra S., Kuperwasser, Charlotte, Cichowski, Karen
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461361/
https://ncbi.nlm.nih.gov/pubmed/27974415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-0520
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