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Induction of 8,5′-Cyclo-2′-deoxyadenosine and 8,5′-Cyclo-2′-deoxyguanosine in Isolated DNA by Fenton-type Reagents
Exposure of aqueous solutions of DNA to X- or γ-rays, which induces hydroxyl radical as one of the major reactive oxygen species (ROS), can result in the generation of a battery of single-nucleobase and bulky DNA lesions. These include the (5′R) and (5′S) diastereomers of 8,5′-cyclo-2′-deoxyadenosin...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3822073/ https://ncbi.nlm.nih.gov/pubmed/23961697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400221w |
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