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Structure of (5′S)-8,5′-Cyclo-2′-Deoxyguanosine in DNA

Diastereomeric 8,5′-cyclopurine 2′-deoxynucleosides, containing a covalent bond between the deoxyribose and the purine base, represent an important class of DNA damage induced by ionizing radiation. The 8,5′-cyclo-2′-deoxyguanosine lesion (cdG) has been recently reported to be a strong block of repl...

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Detalhes bibliográficos
Main Authors: Huang, Hai, Das, Rajat S., Basu, Ashis K., Stone, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279155/
https://ncbi.nlm.nih.gov/pubmed/22103478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja207407n
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