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Repair efficiency of (5’S)-8,5’-cyclo-2’-deoxyguanosine and (5’S)-8,5’-cyclo-2’-deoxyadenosine depends on the complementary base

5’-R and 5’-S diastereoisomers of 8,5’-cyclo-2’-deoxyadenosine (cdA) and 8,5’-cyclo-2’-deoxyguanosine (cdG) containing a base-sugar covalent bond are formed by hydroxyl radicals. R-cdA and S-cdA are repaired by nucleotide excision repair (NER) in mammalian cellular extracts. Here, we have examined s...

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Detalhes bibliográficos
Main Authors: Pande, Paritosh, Das, Rajat S., Sheppard, Clayton, Kow, Yoke W., Basu, Ashis K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3484203/
https://ncbi.nlm.nih.gov/pubmed/23063091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.09.002
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