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Stability of N-glycosidic bond of (5′S)-8,5′-cyclo-2′-deoxyguanosine
8,5′-Cyclopurine deoxynucleosides are unique tandem lesions containing an additional covalent bond between the base and the sugar. These mutagenic and genotoxic lesions are repaired only by nucleotide excision repair. The N-glycosidic (or C1′-N9) bond of 2′-deoxyguanosine (dG) derivatives is usually...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3502650/ https://ncbi.nlm.nih.gov/pubmed/23025578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300302a |
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