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Synthesis of [1,3, NH(2)-(15)N(3)] (5′S)-8,5′-cyclo-2′-deoxyguanosine

In order to facilitate NMR studies and low level detection in biological samples by mass spectrometry, [1,3, NH(2)-(15)N(3)] (5′S)-8,5′-cyclo-2′-deoxyguanosine was synthesized from imidazole-4,5-dicarboxylic acid in twenty-one steps. The three (15)N isotopes were introduced during the chemo-enzymati...

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Bibliografiske detaljer
Udgivet i:J Labelled Comp Radiopharm
Main Authors: Malik, Chanchal K., Das, Rajat S., Basu, Ashis K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382719/
https://ncbi.nlm.nih.gov/pubmed/24285476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3051
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