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Synthesis of [1,3, NH(2)-(15)N(3)] (5′S)-8,5′-cyclo-2′-deoxyguanosine
In order to facilitate NMR studies and low level detection in biological samples by mass spectrometry, [1,3, NH(2)-(15)N(3)] (5′S)-8,5′-cyclo-2′-deoxyguanosine was synthesized from imidazole-4,5-dicarboxylic acid in twenty-one steps. The three (15)N isotopes were introduced during the chemo-enzymati...
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| Publicado no: | J Labelled Comp Radiopharm |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5382719/ https://ncbi.nlm.nih.gov/pubmed/24285476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3051 |
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